Cytoprotection under Oxidative Stress (In Vitro PoC)
Functional proof-of-concept across human and rodent cell systems. Oxidative stress challenges (t-BHP/H₂O₂) in hepatocytes, SH-SY5Y neurons, retinal and cardiac cells. Readouts: viability, ROS, apoptosis via flow cytometry and confocal microscopy. Pharmacodynamics: NRF2-dependent genes and proteins (HMOX1, NQO1).
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