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Proof of Concept in Neurodegeneration (Alzheimer’s & Parkinson’s)

Proof of Concept in Neurodegeneration (Alzheimer’s & Parkinson’s)

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Evaluate NRF2 contribution in translational neurodegenerative models. Alzheimer’s: APP/TAU ± NRF2 models; pathology, neuroinflammation, and behavior. Parkinson’s: MPTP and α-synuclein models; motor and nigrostriatal biomarkers. CNS-NRF2 panel: integration of oxidative stress and inflammasome markers.

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